As our arsenal of antibiotics faces the relentless evolution of resistant microbes, the urgency to fortify our defenses intensifies. In this narrative, we unravel the intricate tapestry of AMR and technological ingenuity flourishing to safeguard the foundations of modern medicine. What is Antimicrobial resistance (AMR)? AMR is a natural process that occurs when microbes (bacteria, viruses, etc) evolve mechanisms that protect them from the effects of antimicrobials (antibiotics, antivirals, etc). Widespread antibiotic resistance is a significant component of AMR. Rise of AMR In 1928, the lucky accident of Penicillin discovery in Alexander Fleming's London laboratory changed the course of medicine. Ten years after its discovery - in 1939, extensive research began on Penicillin. It led to the establishment of “The Penicillin Project” - a collaboration that brought 15 pharmaceutical companies in the USA and the UK together to produce Penicillin. The first trials of Penicillin were c